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By making a pre-emptive announcement, and offering reasons and justifications, Sharapova has taken risks. 2003 Jun 1; 91 (11): 1327-1330 and Does subclinical hypothyroidism affect cardiac pump performance? A 2010 European Federation of Neurological Societies task force clinical guideline based on available evidence recommended gabapentin as a first-line treatment for diabetic neuropathy and postherpetic neuralgia with its highest level of evidence; it also recommended gabapentin as a first-line treatment for central pain but with lower evidence.

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We know that there's a hormonal component, and it's also mediated by neurotransmitters, specifically dopamine and serotonin, and the way that they act in the frontal cortex." The most recent edition of Diagnostic and Statistical Manual of Mental Disorders, the DSM-5, which came out in 2013, changed things around, and HSDD is no longer a standalone diagnosis.

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